IL-12B p40 Polyclonal Antibody, 50ul Subcellular Fractions RAB11FIP3 (RAB11 family interacting protein

RAB11FIP3 (RAB11 family interacting protein 3) is one of many proteins that interact with and regulate Rab GTPases

Mutations in CASP10 are associated with type IIA autoimmune lymphoproliferative syndrome

This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined

An important paralog of this gene is KBTBD4

The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids

IL-12B p40 Polyclonal Antibody, 50ul Subcellular Fractions RAB11FIP3 (RAB11 family interacting proteinThis gene encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to