Raf-1(Phospho Ser621) Polyclonal Antibody, 50ul ssDNA Synthesis Cleavage of the precursor generates

Cleavage of the precursor generates alpha and beta subunits

Interacts with the oligomeric lectins MBL2| FCN2 and FCN3

which suggests its role in PI(3) kinase-mediated signaling events

MAPKAPK2 (mitogen-activated protein kinase-activated protein kinase 2) encodes a member of the Ser/Thr protein kinase family

This gene encodes a member of the patatin-like phospholipase domain containing protein family

Raf-1(Phospho Ser621) Polyclonal Antibody, 50ul ssDNA Synthesis Cleavage of the precursor generatesThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.