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RPA40 Polyclonal Antibody, 100ul Culture Tubes Multiple alternatively spliced transcript variants

SKU: 63671748568

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RPA40 Polyclonal Antibody, 100ul Culture Tubes Multiple alternatively spliced transcript variantsThe protein encoded by POLR1C (RNA polymerase I subunit C) is a subunit of both RNA polymerase I and RNA polymerase III complexes. The encoded protein is part of the Pol core element. Mutations in POLR1C have been associated with Treacher Collins syndrome (TCS) and hypomyelinating leukodystrophy 11. Alternative splicing results in multiple transcript variants.

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Description

Multiple alternatively spliced transcript variants have been observed that encode distinct proteins

In response to cellular metabolic stresses

BTB/POZ proteins are involved in several cellular processes including proliferation

SMG7 encodes protein SMG7 that is essential for nonsense-mediated mRNA decay (NMD)

Interacts with PEBP2-alpha subunit| CREB-binding protein (CBP)| p300| SMURF1| SMURF2 and HOXC8

RPA40 Polyclonal Antibody, 100ul Culture Tubes Multiple alternatively spliced transcript variantsThe protein encoded by POLR1C (RNA polymerase I subunit C) is a subunit of both RNA polymerase I and RNA polymerase III complexes. The encoded protein is part of the Pol core element. Mutations in POLR1C have been associated with Treacher Collins syndrome (TCS) and hypomyelinating leukodystrophy 11. Alternative splicing results in multiple transcript variants.

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