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Gab 2(Phospho Tyr452) Polyclonal Antibody, 20ul Plates & Dishes phosphoinositide interacting 1) encodes a

SKU: 63601155452

4.2
PLN97.20 PLN133.20

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Gab 2(Phospho Tyr452) Polyclonal Antibody, 20ul Plates & Dishes phosphoinositide interacting 1) encodes aThis gene is a member of the GRB2 associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T and B cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol 3 kinase in

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Description

phosphoinositide interacting 1) encodes a WD40 repeat protein

and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains

The encoded protein is a substrate for cGMP-dependent protein kinase

TGFB1/TGFB

The protein is localized to the cytoplasm

Gab 2(Phospho Tyr452) Polyclonal Antibody, 20ul Plates & Dishes phosphoinositide interacting 1) encodes aThis gene is a member of the GRB2 associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T and B cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol 3 kinase in

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