PASD1 Rabbit Polyclonal Antibody, 100ul Biochemical Reagents Mutations in KRT18 have been

Mutations in KRT18 have been linked to cryptogenic cirrhosis

the retinoic acid receptor-related orphan receptors and the vitamin D receptors

The protein encoded by this gene is the beta subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase

An important paralog of this gene is MPND

The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1

PASD1 Rabbit Polyclonal Antibody, 100ul Biochemical Reagents Mutations in KRT18 have beenThis gene encodes a protein that is thought to function as a transcription factor. The protein is a cancer associated antigen that can stimulate autologous T cell responses and it is therefore considered to be a potential immunotherapeutic target for the treatment of various hematopoietic malignancies including diffuse large B cell lymphoma.