HDAC5/9 Polyclonal Antibody, 20ul Cellular Cultivation & Health Management The protein localizes to the

The protein localizes to the nucleus

It is localized in the Down syndrome critical region of chromosome 21

The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal

An important paralog of this gene is SNAPC4

and its synthesis and secretion are stimulated in vitro by incubating cells with apoA-I

HDAC5/9 Polyclonal Antibody, 20ul Cellular Cultivation & Health Management The protein localizes to theHistones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation deacetylation alters chromosome structure and affects transcription factor access to DNA. Histone deacetylase 5 encoded by HDAC5 belongs to the class II histone deacetylase acuc apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with