EphA10 Polyclonal Antibody, 50ul Mechanical Pipette This gene is present in

This gene is present in a gene cluster with other members of the ADAM family on chromosome 8

Its expression is thought to be restricted to striated muscle

Unlike most MMP family members

Defects in this gene are a cause of regulator type Rh-null hemolytic anemia (RHN)

Expression of TPD52L2 may be a marker for breast cancer and acute lymphoblastic leukemia

EphA10 Polyclonal Antibody, 50ul Mechanical Pipette This gene is present inEphrin receptors, the largest subfamily of receptor tyrosine kinases (RTKs), and their ephrin ligands are important mediators of cell cell communication regulating cell attachment, shape, and mobility in neuronal and epithelial cells (Aasheim et al. 2005 [PubMed 15777695]). See MIM 179610 for additional background on Eph receptors and ephrins.