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FAK(Phospho Tyr577) Polyclonal Antibody, 50ul Liquid Handling &Storage and has been shown to

SKU: 61336067720

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FAK(Phospho Tyr577) Polyclonal Antibody, 50ul Liquid Handling &Storage and has been shown toThis gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal

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Description

and has been shown to stimulate the production of several other cytokines

Cleavage of the precursor generates alpha and beta subunits

PKC family members also serve as major receptors for phorbol esters

which may be important for the cellular response to DNA damage

An important paralog of this gene is HSH2D

FAK(Phospho Tyr577) Polyclonal Antibody, 50ul Liquid Handling &Storage and has been shown toThis gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal

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