TCAL8 Polyclonal Antibody, 20ul Custom DNA Oligos INTS2 (integrator complex subunit 2)

INTS2 (integrator complex subunit 2) is a subunit of the Integrator complex

Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I

Translocations involving this gene and the ret proto-oncogene have been found in tumor tissues

enhances the generation of cytolytic T cells

It may function as a bridge molecule between BCL2 and ARHGAP1/CDC42 in promoting cell death

TCAL8 Polyclonal Antibody, 20ul Custom DNA Oligos INTS2 (integrator complex subunit 2)This gene encodes a member of the transcription elongation factor A (SII) like (TCEAL) gene family. Members of this family contain TFA domains and may function as nuclear phosphoproteins that modulate transcription in a promoter context dependent manner. Multiple family members are located on the X chromosome. Alternative splicing results in multiple transcript variants encoding a single isoform.