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TRPM2 Rabbit Polyclonal Antibody, 50ul 3D Cell Culture Consumables NONO and MATR3

SKU: 59493651273

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TRPM2 Rabbit Polyclonal Antibody, 50ul 3D Cell Culture Consumables NONO and MATR3The protein encoded by this gene forms a tetrameric cation channel that is permeable to calcium sodium and potassium and is regulated by free intracellular ADP ribose. The encoded protein is activated by oxidative stress and confers susceptibility to cell death. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms. Additional transcript variants of this gene have been described but their full length nature is

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Description

NONO and MATR3

Phosphorylation by GSK3B may negatively regulate binding to microtubule lattices in lamella

Mutations in this gene are associated with nail-patella syndrome

Ser-1029 or Ser-1031 is important for cytoplasmic export

and thus to a rapid reduction of translational initiation and repression of global protein synthesis

TRPM2 Rabbit Polyclonal Antibody, 50ul 3D Cell Culture Consumables NONO and MATR3The protein encoded by this gene forms a tetrameric cation channel that is permeable to calcium sodium and potassium and is regulated by free intracellular ADP ribose. The encoded protein is activated by oxidative stress and confers susceptibility to cell death. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms. Additional transcript variants of this gene have been described but their full length nature is

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