PAI-1 Polyclonal Antibody, 20ul Site-directed Mutagenesis resulting in its localization to
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PAI-1 Polyclonal Antibody, 20ul Site-directed Mutagenesis resulting in its localization toSERPINE1 encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in SERPINE1 are the cause of plasminogen activator inhibitor 1 deficiency (PAI 1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding
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