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Stat2 (Acetyl Lys384) Rabbit Polyclonal Antibody, 50ul In vitro Assessment Interacts with RIP and XPA

SKU: 58301736285

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Stat2 (Acetyl Lys384) Rabbit Polyclonal Antibody, 50ul In vitro Assessment Interacts with RIP and XPASignal transducer and activator of transcription that mediates signaling by type I IFNs (IFN alpha and IFN beta). Following type I IFN binding to cell surface receptors Jak kinases (TYK2 and JAK1) are activated leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize associate with ISGF3G IRF 9 to form a complex termed ISGF3 transcription factor that enters the nucleus. ISGF3 binds to the IFN stimulated response

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Description

Interacts with RIP and XPA

and are critical for cell-cell interaction

Appears to function synergistically with RBM14 as a transcriptional coactivator

The genes in this cluster encode members of the cancer/testis (CT) family of antigens| and are distinct from other CT antigens

MARK proteins phosphorylate MAPs within their microtubule binding domains

Stat2 (Acetyl Lys384) Rabbit Polyclonal Antibody, 50ul In vitro Assessment Interacts with RIP and XPASignal transducer and activator of transcription that mediates signaling by type I IFNs (IFN alpha and IFN beta). Following type I IFN binding to cell surface receptors Jak kinases (TYK2 and JAK1) are activated leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize associate with ISGF3G IRF 9 to form a complex termed ISGF3 transcription factor that enters the nucleus. ISGF3 binds to the IFN stimulated response

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