SHIP-2 Polyclonal Antibody, 100ul Protein Post-translational Modification BinCARD plays a role in

BinCARD plays a role in inhibiting the effects of Bcl10-induced activation of NFκB possibly by inhibiting the phosphorylation of Bcl10 in a CARD-dependent manner

Mutations in this gene cause the autosomal recessive leukocyte adhesion deficiency syndrome-III (LAD-III)

The protein encoded by this gene is an exceedingly potent mediator of new blood vessel formation

three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats

Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing to generate mature polypeptides

SHIP-2 Polyclonal Antibody, 100ul Protein Post-translational Modification BinCARD plays a role inPhosphatidylinositol 3,4,5 trisphosphate 5 phosphatase 2 encoded by INPPL1 is an SH2 containing 5' inositol phosphatase that is involved in the regulation of insulin function. The encoded protein also plays a role in the regulation of epidermal growth factor receptor turnover and actin remodelling. Additionally, this gene supports metastatic growth in breast cancer and is a valuable biomarker for breast cancer.