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IGF2 Polyclonal Antibody, 100ul Centrifugal Filter This gene encodes a cytokine

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IGF2 Polyclonal Antibody, 100ul Centrifugal Filter This gene encodes a cytokineThis gene encodes a member of the insulin family of polypeptide growth factors which are involved in development and growth. It is an imprinted gene expressed only from the paternal allele and epigenetic changes at this locus are associated with Wilms tumour Beckwith Wiedemann syndrome rhabdomyosarcoma and Silver Russell syndrome. A read through INS IGF2 gene exists whose 5' region overlaps the INS gene and the 3' region overlaps this gene.

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Description

This gene encodes a cytokine distantly related to type I interferons and the IL-10 family

Mutations in this gene have been found in somatic sebaceous tumors

and a cytoplasmic tail with three conserved signaling motifs: CC0

It mediates E3-dependent ubiquitination and proteasomal degradation of target proteins

LZIP (also designated CREB3 and Luman)

IGF2 Polyclonal Antibody, 100ul Centrifugal Filter This gene encodes a cytokineThis gene encodes a member of the insulin family of polypeptide growth factors which are involved in development and growth. It is an imprinted gene expressed only from the paternal allele and epigenetic changes at this locus are associated with Wilms tumour Beckwith Wiedemann syndrome rhabdomyosarcoma and Silver Russell syndrome. A read through INS IGF2 gene exists whose 5' region overlaps the INS gene and the 3' region overlaps this gene.

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