hnRNP K(Phospho Ser284) Polyclonal Antibody, 20ul Serum & Sample Tubes This gene has been described

This gene has been described as both a tumor suppressor and an oncogene depending on the cellular context

A translocation involving this gene on chromosome X and the homolog of the Drosophila trithorax gene| encoding a DNA binding protein| located on chromosome 11 is associated with leukemia

and thus induce cell cycle arrest

and a pseudogene of MED27 is located on the long arm of chromosome 5

The encoded protein also has phospholipase C activity

hnRNP K(Phospho Ser284) Polyclonal Antibody, 20ul Serum & Sample Tubes This gene has been describedThis gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre mRNAs in the nucleus and appear to influence pre mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus