N4BP2 Rabbit Polyclonal Antibody, 20ul Live Cell Imaging PIAS proteins function as SUMO

PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins

The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2

An important paralog of this gene is USP4

The WFIKKN1 protein contains a WAP domain| follistatin domain| immunoglobulin domain| two tandem Kunitz domains| and an NTR domain

It can deubiquitinate H2A

N4BP2 Rabbit Polyclonal Antibody, 20ul Live Cell Imaging PIAS proteins function as SUMOThis gene encodes a protein containing a polynucleotide kinase domain (PNK) near the N terminal region and a Small MutS Related (Smr) domain near the C terminal region. The encoded protein can bind to both B cell leukemia lymphoma 3 (BCL 3) and neural precursor cell expressed developmentally downregulated 4 (Nedd4) proteins. This protein binds and hydrolyzes ATP may function as a 5' polynucleotide kinase and has the capacity to be a ubiquitylation