ATF6A Rabbit Polyclonal Antibody, 50ul Bio-Reaction Tube Diseases associated with OPRD1 include

Diseases associated with OPRD1 include morphine dependence and heroin dependence

which suggest the roles of this kinase in stress related transcription and cell cycle regulation

moderate expression is found in amygdala and caudate nucleus

transcription regulation

CEBPG and ATF2 thereby inhibiting transactivation by JUN

ATF6A Rabbit Polyclonal Antibody, 50ul Bio-Reaction Tube Diseases associated with OPRD1 includeThis gene encodes a transcription factor that activates target genes for the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Although it is a transcription factor, this protein is unusual in that it is synthesized as a transmembrane protein that is embedded in the ER. It functions as an ER stress sensor transducer, and following ER stress induced proteolysis, it functions as a nuclear transcription factor via a cis acting ER