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GRK 4 Polyclonal Antibody, 50ul Centrifuge Tube (Bottle) The product of this gene

SKU: 51343089902

4.3
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GRK 4 Polyclonal Antibody, 50ul Centrifuge Tube (Bottle) The product of this geneGRK4 encodes a member of the guanine nucleotide binding protein (G protein) coupled receptor kinase subfamily of the Ser Thr protein kinase family. The protein phosphorylates the activated forms of G protein coupled receptors thus initiating its deactivation. This gene has been linked to both genetic and acquired hypertension. Several transcript variants encoding different isoforms have been found for this gene.

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Description

The product of this gene forms homomeric complexes and heteromeric complexes with other activated Smad proteins

Alternative splicing results in four transcript variants encoding the same protein

A similar protein in mouse is thought to regulate differentiation and proliferation of cells in the colon

and a C-terminal region containing multiple XFXFG repeats

In response to BMP ligands| this protein can be phosphorylated and activated by the BMP receptor kinase

GRK 4 Polyclonal Antibody, 50ul Centrifuge Tube (Bottle) The product of this geneGRK4 encodes a member of the guanine nucleotide binding protein (G protein) coupled receptor kinase subfamily of the Ser Thr protein kinase family. The protein phosphorylates the activated forms of G protein coupled receptors thus initiating its deactivation. This gene has been linked to both genetic and acquired hypertension. Several transcript variants encoding different isoforms have been found for this gene.

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