p53 Polyclonal Antibody, 50ul[BT-AP06815] Site-directed Mutagenesis Mutations in this gene have

Mutations in this gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency

The protein encoded by this gene is a nuclear outer membrane protein that binds cytoplasmic F-actin

In these cells

The D-5 position also can be phosphorylated by type I PtdIns4P-5-kinases (PIP5Ks) that are encoded by distinct genes and preferentially phosphorylate D-4 phosphorylated PtdIns

Under stress conditions

p53 Polyclonal Antibody, 50ul[BT-AP06815] Site-directed Mutagenesis Mutations in this gene haveTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.