FAK Rabbit Polyclonal Antibody, 50ul Gloves The type II isozyme

The type II isozyme

This domain is known to be involved in protein-protein interactions

An important paralog of this gene is SERPINA12

The protein encoded by this gene is a transcription factor of the PR-domain protein family

Mutations in this gene are associated with Keppen-Lubinsky Syndrome

FAK Rabbit Polyclonal Antibody, 50ul Gloves The type II isozymeThis gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal