Phospho-53BP1 (S6) Polyclonal Antibody, 50ul Serum Several alternatively spliced transcript variants

Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene

acts as a cofactor that increases p53/TP53 response via its interaction with p300/EP300

It was also reported to play a key role as an initiator of the mRNA degradation machinery in the recycling of ribosomes in successive cycles of translation

Plays a role in mitotic exit and cytokinesis

allowing depolarization of rod photoreceptors

Phospho-53BP1 (S6) Polyclonal Antibody, 50ul Serum Several alternatively spliced transcript variantsTP53BP1 (Tumor Protein P53 Binding Protein 1) is a Protein Coding gene. Diseases associated with TP53BP1 include riddle syndrome and ataxia telangiectasia. Among its related pathways are DNA Damage and ATM Pathway. GO annotations related to this gene include sequence specific DNA binding and p53 binding.