Rat Intercellular Adhesion Molecule 1, ICAM-1 ELISA Kit, 96T Human Genome Knockout Libraries Increased transcriptional expression of POT1

Increased transcriptional expression of POT1 is associated with stomach carcinogenesis and its progression

The product of this gene belongs to the ligand-gated ion channel receptor superfamily

Surfeit locus protein 1 is a member of the SURF1 family

which act as platforms for receptor clustering and signaling

May also regulate neurite outgrowth by activating the FGFR1 signaling pathway

Rat Intercellular Adhesion Molecule 1, ICAM-1 ELISA Kit, 96T Human Genome Knockout Libraries Increased transcriptional expression of POT1ICAM proteins are ligands for the leukocyte adhesion protein LFA 1 (integrin alpha L beta 2). During leukocyte trans endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26 SGEF and RHOG activation (By similarity).