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Phospho-C3G (Y504) Polyclonal Antibody, 100ul Peripheral Blood Separation Tube also known as HP43

SKU: 47433393404

4.4
PLN141.00 PLN186.00

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Phospho-C3G (Y504) Polyclonal Antibody, 100ul Peripheral Blood Separation Tube also known as HP43RAPGEF1 encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full length nature of some variants has not been

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Description

also known as HP43

It is thought to play a critical role in directing Hsp90 to its target kinases

translocation events resulting in gene fusions of this gene with both DUX4 (GeneID:100288687) and FOXO4 (GeneID:4303) have been associated with round cell sarcomas

3 region which is commonly deleted in neuroblastomas

GO annotations related to this gene include peptidase activity and aminopeptidase activity

Phospho-C3G (Y504) Polyclonal Antibody, 100ul Peripheral Blood Separation Tube also known as HP43RAPGEF1 encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full length nature of some variants has not been

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