Rb Polyclonal Antibody, 20ul[BT-AP07688] Yeast Expression It has been suggested that

It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer

and not responsive to ADP

An important paralog of this gene is UBA52

This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system

NFKB1 encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein

Rb Polyclonal Antibody, 20ul[BT-AP07688] Yeast Expression It has been suggested thatThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.