PDX-1 Polyclonal Antibody, 50ul Site-directed Mutagenesis a region which confers cyclic

a region which confers cyclic nucleotide regulation of message decay

it ensures optimal cell growth and viability

The encoded protein is located in the nucleus

while defects in this gene are associated with multiple types of cancer

a member of the RAS oncogene family

PDX-1 Polyclonal Antibody, 50ul Site-directed Mutagenesis a region which confers cyclicThe protein encoded by PDX1 is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early onset insulin dependent