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IκB-beta(Phospho Ser23) Polyclonal Antibody, 20ul Mechanical Pipette Seems to play a role

SKU: 45320202225

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IκB-beta(Phospho Ser23) Polyclonal Antibody, 20ul Mechanical Pipette Seems to play a roleThe protein encoded by this gene belongs to the NF kappa B inhibitor family, which inhibit NF kappa B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF kappa B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been

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Description

Seems to play a role as an inhibitor of apoptosis

The encoded protein catalyzes the conversion of diacylglycerol and fatty acyl CoA to triacylglycerol

and has been implicated in development of prostate cancer cells

Knockout mice lacking this gene show that it is required for retinal cone bipolar cell differentiation| and that it negatively regulates potassium channel gene expression in the heart to ensure coordinated cardiac repolarization

This gene is a member of the roadblock dynein light chain family

IκB-beta(Phospho Ser23) Polyclonal Antibody, 20ul Mechanical Pipette Seems to play a roleThe protein encoded by this gene belongs to the NF kappa B inhibitor family, which inhibit NF kappa B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF kappa B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been

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