Phospho PKC theta (Y90) Rabbit Polyclonal Antibody, 20ul Antibodies suggesting that it functions as

suggesting that it functions as a transcription factor

However| the requirement for furin cleavage in this process remains controversial based on mouse studies

In addition| this subunit| in combination with several other polymerase subunits| forms the DNA binding domain of the polymerase| a groove in which the DNA template is transcribed into RNA

and may be involved in pancreatic lithogenesis

This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription

Phospho PKC theta (Y90) Rabbit Polyclonal Antibody, 20ul Antibodies suggesting that it functions asCatalytic activity: ATP + a protein = ADP + a phosphoprotein. cofactor: Magnesium. The C1 domain containing the phorbol ester DAG type region 1 (C1A) and 2 (C1B) is the diacylglycerol sensor and the C2 domain is a non calcium binding domain. enzyme regulation: Three specific sites; Thr 538 (activation loop of the kinase domain) Ser 676 (turn motif) and Ser 695 (hydrophobic region) need to be phosphorylated for its full activation. PKC is activated by