Topo II alpha(Phospho Ser1106) Polyclonal Antibody, 100ul Human Genome Knockout Libraries fibrinogen is cleaved by thrombin

fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots

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May control smooth muscle cells proliferation following artery injury through PDGFA repression

Two transcript variants encoding different isoforms have been described for this gene

Transcript variants resulted from an alternative promoter and alternative splicings have been found| which overlap the current reference sequence and has several exons upstream and downstream of the current reference sequence

Topo II alpha(Phospho Ser1106) Polyclonal Antibody, 100ul Human Genome Knockout Libraries fibrinogen is cleaved by thrombinThis gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus