Human Isocitrate Dehydrogenase, Nadp, Mitochondrial, IDH2 ELISA Kit, 96T Peptide Modification MSTN encodes a secreted ligand

MSTN encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins

Acts as a transcriptional coactivator of serum response factor (SRF)

The phosphorylation of MYOD1 enhances its transcriptional activity and thus promotes muscle differentiation (PubMed: 12037670)

Can bent DNA and enhance DNA flexibility by looping thus providing a mechanism to promote activities on various gene promoters by enhancing transcription factor binding and/or bringing distant regulatory sequences into close proximity (PubMed: 20123072)

and the chains are extruded through pore-like structures into the extracellular space

Human Isocitrate Dehydrogenase, Nadp, Mitochondrial, IDH2 ELISA Kit, 96T Peptide Modification MSTN encodes a secreted ligand