HMGB3 Rabbit Polyclonal Antibody, 100ul Miscellaneous Chromosome 8 is also associated

Chromosome 8 is also associated with Pfeiffer syndrome

Mutations in this gene lead to Jackson-Lawler type pachyonychia congenita and steatocystoma multiplex

PRSS33 (Protease

also called the 'RING-B-box-coiled-coil' (RBCC) subgroup of RING finger proteins

They function as carriers to the cell surface in post-golgi recycling pathways

HMGB3 Rabbit Polyclonal Antibody, 100ul Miscellaneous Chromosome 8 is also associatedThis gene encodes a member of a family of proteins containing one or more high mobility group DNA binding motifs. The encoded protein plays an important role in maintaining stem cell populations and may be aberrantly expressed in tumor cells. A mutation in this gene was associated with microphthalmia syndromic 13. There are numerous pseudogenes of this gene on multiple chromosomes. Alternative splicing results in multiple transcript variants.