CHOP(Phospho Ser30) Polyclonal Antibody, 50ul Custom Peptide Synthesis CBX2 (chromobox 2) encodes a

CBX2 (chromobox 2) encodes a component of the polycomb multiprotein complex

Multiple phosphorylation sites have been identified: ser297 and Ser392 mediate 14-3-3 binding

PTM:Autophosphorylated on both serine and threonine residues (By similarity)

It requires divalent metal ions and an intact Nudix motif for enzymatic activity

lymph node

CHOP(Phospho Ser30) Polyclonal Antibody, 50ul Custom Peptide Synthesis CBX2 (chromobox 2) encodes aThis gene encodes a member of the CCAAT enhancer binding protein (C EBP) family of transcription factors. The protein functions as a dominant negative inhibitor by forming heterodimers with other C EBP members, such as C EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene