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NuMA Polyclonal Antibody, 50ul High Speed Micro-Centrifuges CBX5 encodes a highly conserved

SKU: 40587178985

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NuMA Polyclonal Antibody, 50ul High Speed Micro-Centrifuges CBX5 encodes a highly conservedNUMA1 encodes a large protein that forms a structural component of the nuclear matrix. The encoded protein interacts with microtubules and plays a role in the formation and organization of the mitotic spindle during cell division. Chromosomal translocation of NUMA1 with the RARA (retinoic acid receptor, alpha) gene on chromosome 17 have been detected in patients with acute promyelocytic leukemia. Alternative splicing results in multiple transcript

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Description

CBX5 encodes a highly conserved nonhistone protein

Seems to play an essential role in cold-induced suppression of cell proliferation

The protein binds to collagen IV and laminin

Mutations in the gene are associated with localized autosomal recessive hypotrichosis and monilethrix

Involved in formation of membrane ruffles and lamellipodia protrusions and in axon outgrowth

NuMA Polyclonal Antibody, 50ul High Speed Micro-Centrifuges CBX5 encodes a highly conservedNUMA1 encodes a large protein that forms a structural component of the nuclear matrix. The encoded protein interacts with microtubules and plays a role in the formation and organization of the mitotic spindle during cell division. Chromosomal translocation of NUMA1 with the RARA (retinoic acid receptor, alpha) gene on chromosome 17 have been detected in patients with acute promyelocytic leukemia. Alternative splicing results in multiple transcript

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