UBC Rabbit Polyclonal Antibody, 20ul Recombinant Protein Expression SAE1 (MIM 613294) and UBA2

SAE1 (MIM 613294) and UBA2 form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins

Transcript variants using alternative promoters or polyA sites have been mentioned in the literature but the complete description of these sequences is not available

Rho guanine nucleotide exchange factor 2 may form complex with G proteins and stimulate rho-dependent signals

Expressed in a variety of tissues with highest expression in testis and brain

GO annotations related to this gene include cation transmembrane transporter activity and calcium channel inhibitor activity

UBC Rabbit Polyclonal Antibody, 20ul Recombinant Protein Expression SAE1 (MIM 613294) and UBA2This gene represents a ubiquitin gene ubiquitin C. The encoded protein is a polyubiquitin precursor. Conjugation of ubiquitin monomers or polymers can lead to various effects within a cell depending on the residues to which ubiquitin is conjugated. Ubiquitination has been associated with protein degradation DNA repair cell cycle regulation kinase modification endocytosis and regulation of other cell signaling pathways.