TAF10 Polyclonal Antibody, 50ul Variant Libraries and may be involved in

and may be involved in human cancer

The encoded protein| which belongs to the groucho/TLE family of proteins| can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes

Defects in this gene are the cause of faciogenital dysplasia and X-linked mental retardation| syndromatic 16

GTP-bound Rho to the inactive GDP-bound form by RhoGAP

There is a read-through locus (GeneID: 100526761) that shares sequence identity with this gene and the upstream CCDC169 (GeneID: 728591)

TAF10 Polyclonal Antibody, 50ul Variant Libraries and may be involved inInitiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA binding protein (TBP) and a group of