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ASK 1 Polyclonal Antibody, 100ul[BT-AP00672] Human Genome Knockout Libraries This gene encodes a major

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SEK141.00 SEK172.00

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ASK 1 Polyclonal Antibody, 100ul[BT-AP00672] Human Genome Knockout Libraries This gene encodes a majorMitogen activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MAPKKK5 contains

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Description

This gene encodes a major subunit of the RAL-GTPase activating protein

Naturally occuring readthrough transcription occurs between this locus and the downstream GNMT (glycine N-methyltransferase) gene and is represented with GeneID:107080644

This protein can form homodimers or can heterodimerize with another photoreceptor| retinal degeneration slow (RDS)

Alternative splicing has been observed at this locus and two variants

The encoded protein undergoes an initial autocatalytic processing event in the ER and then sorts to the trans-Golgi network through endosomes where a second autocatalytic event takes place and the Catalytic activity is acquired

ASK 1 Polyclonal Antibody, 100ul[BT-AP00672] Human Genome Knockout Libraries This gene encodes a majorMitogen activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MAPKKK5 contains

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