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NEDD4L(Phospho-Ser448) Rabbit Polyclonal Antibody, 20ul PCR Series It is part of a

SKU: 35877435361

4.4
PLN111.00 PLN137.00

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NEDD4L(Phospho-Ser448) Rabbit Polyclonal Antibody, 20ul PCR Series It is part of aThis gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin conjugating enzymes to protein substrates thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial

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Description

It is part of a gene cluster on chromosome Xp11

This gene is a candidate gene for Hirschsprung disease

The enzymes display overlapping but distinct substrate specificity

The tripartite motif containing 38 contains a RING-type zinc finger

This protein is a member of the MRP subfamily that is involved in multi-drug resistance

NEDD4L(Phospho-Ser448) Rabbit Polyclonal Antibody, 20ul PCR Series It is part of aThis gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin conjugating enzymes to protein substrates thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial

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