FA8A Rabbit Polyclonal Antibody, 50ul[BT-AP02610] Proteases Multiple splice variants encoding different

Multiple splice variants encoding different isoforms have been found for this gene

It is thought to play a critical role in directing Hsp90 to its target kinases

MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease| Pick's disease| frontotemporal dementia| cortico-basal degeneration and progressive supranuclear palsy

The encoded protein is required for the ubiquitination and subsequent degradation of the anti-apoptotic protein Mcl1 (myeloid cell leukemia sequence 1 (BCL2-related))

This gene shares a common promoter with metaxin 1

FA8A Rabbit Polyclonal Antibody, 50ul[BT-AP02610] Proteases Multiple splice variants encoding differentdisease: Defects in F8 are the cause of hemophilia A (HEMA)