ASPP1 Polyclonal Antibody, 50ul Organelle Studies However| this gene product contains

However| this gene product contains a KRAB domain (which is involved in protein-protein interactions) at the N-terminus| and a transposase domain at the C-terminus| suggesting that it may belong to the family of DNA-mediated transposons in human

In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon

Three subunits (alpha| beta and gamma) of the 11S regulator have been identified

which is included in the cadherin superfamily

and the protein is the target for neurodegeneration induced by organophosphorus compounds and chemical warfare agents

ASPP1 Polyclonal Antibody, 50ul Organelle Studies However| this gene product containsThis gene encodes a member of the ASPP (apoptosis stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein protein interactions. ASPP proteins are required for the induction of apoptosis by p53 family proteins. They promote DNA binding and transactivation of p53 family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F