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CD6 Polyclonal Antibody, 20ul[BT-AP02272] Capsule Filter Take your research to newCOP9 signalosome subunit 3 encoded by COPS3 possesses kinase activity that phosphorylates regulators involved in signal transduction. It phosphorylates I kappa Balpha, p105, and c Jun. It acts as a docking site for complex mediated phosphorylation. The gene is located within the Smith Magenis syndrome region on chromosome 17. Several transcript variants encoding different isoforms have been found for COPS3.