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DNA pol Delta cat Polyclonal Antibody, 100ul Subcellular Fractions The protein encoded by this

SKU: 33185504967

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DNA pol Delta cat Polyclonal Antibody, 100ul Subcellular Fractions The protein encoded by thisPOLD1 (DNA polymerase delta 1, catalytic subunit) encodes the 125 kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 6.

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Description

The protein encoded by this gene is a member of the IRS1-like multisubstrate docking protein family

5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor

Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment

or fibronectin

Mutations in this gene have been associated with microphthalmia

DNA pol Delta cat Polyclonal Antibody, 100ul Subcellular Fractions The protein encoded by thisPOLD1 (DNA polymerase delta 1, catalytic subunit) encodes the 125 kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 6.

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