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NCKX2 Polyclonal Antibody, 50ul Gel & Buffers Mutations in this gene have

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NCKX2 Polyclonal Antibody, 50ul Gel & Buffers Mutations in this gene haveThis gene encodes a member of the calcium cation antiporter superfamily of transport proteins. The encoded protein belongs to the SLC24 branch of exchangers, which can mediate the extrusion of one Ca2+ ion and one K+ ion in exchange for four Na+ ions. This family member is a retinal cone brain exchanger that can mediate a light induced decrease in free Ca2+ concentration. This protein may also play a neuroprotective role during ischemic brain injury.

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Description

Mutations in this gene have been associated with neonatal diabetes and congenital hypothyroidism (NDH)

FOXN2 encodes a forkhead domain binding protein and may function in the transcriptional regulation of the human T-cell leukemia virus long terminal repeat

Marked reduction in this protein has been observed in association with Alzheimer's disease

MIM 186910)-positive T cells and encodes a type I transmembrane protein with V and C1-like Ig domains (Yeh et al

has not yet been determined

NCKX2 Polyclonal Antibody, 50ul Gel & Buffers Mutations in this gene haveThis gene encodes a member of the calcium cation antiporter superfamily of transport proteins. The encoded protein belongs to the SLC24 branch of exchangers, which can mediate the extrusion of one Ca2+ ion and one K+ ion in exchange for four Na+ ions. This family member is a retinal cone brain exchanger that can mediate a light induced decrease in free Ca2+ concentration. This protein may also play a neuroprotective role during ischemic brain injury.

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