NFKappaB-p65 Polyclonal Antibody, 50ul[BT-AP05997] Polyclonal Antibody Preparation This protein displays E3 ubiquitin

This protein displays E3 ubiquitin ligase activity toward the cyclin-dependent kinase inhibitor 1B which is also known as p27 or KIP1

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The mouse ortholog of this gene is specifically expressed in germ cells at the round spermatid stages during spermatogenesis and| when overexpressed| induces apoptosis

Inhibits the transcriptional activation mediated by PAX5

Polymorphisms in this gene may be associated with a susceptibility for schizophrenia

NFKappaB-p65 Polyclonal Antibody, 50ul[BT-AP05997] Polyclonal Antibody Preparation This protein displays E3 ubiquitinNF kappa B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF kappa B moves to the nucleus and activates transcription of specific genes. NF kappa B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF kappa B is NFKB1 complexed with the product of RELA, RELA. Four