MARCH1 Polyclonal Antibody, 20ul Centrifuge Tube (Bottle) The kinases of these signaling

The kinases of these signaling cascades are highly conserved

on the benchtop or even beneath the bench

It is enriched in the basement membrane of muscles at the neuromuscular junctions

May promote the rapid formation of a branched actin network by first nucleating new mother filaments and then activating Arp2/3 to branch off these filaments

An important paralog of this gene is IQGAP1

MARCH1 Polyclonal Antibody, 20ul Centrifuge Tube (Bottle) The kinases of these signalingMARCH1 (membrane associated ring CH type finger 1) is a member of the MARCH family of membrane bound E3 ubiquitin ligases. MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH1 downregulates the surface expression of major histocompatibility complex (MHC) class II molecules (see MIM 142880) and other glycoproteins by directing them to the