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AKAP4 Polyclonal Antibody, 20ul Dialysis alternative products:Isoforms differ in the

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AKAP4 Polyclonal Antibody, 20ul Dialysis alternative products:Isoforms differ in theThe A kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is localized to the sperm flagellum and may be involved in the regulation of sperm motility. Alternative splicing of this gene results in two

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alternative products:Isoforms differ in the N- and C-termini|Catalytic activity:Strict requirement for an Asp residue at P1| with 316-asp being essential for proteolytic activity and has a preferred cleavage sequence of Val-Asp-Val-Ala-Asp-|-

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Polymorphisms in this gene are associated with diabetes

AKAP4 Polyclonal Antibody, 20ul Dialysis alternative products:Isoforms differ in theThe A kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is localized to the sperm flagellum and may be involved in the regulation of sperm motility. Alternative splicing of this gene results in two

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