Vav1(Phospho Tyr174) Polyclonal Antibody, 50ul Funnels Interacts with the phosphorylated carboxyterminal

Interacts with the phosphorylated carboxyterminal domain of POLR2A

Multiple alternatively spliced transcript variants differring in the 5' UTR have been described| but the full-length nature of these variants has not been determined

MIM 131550) to initiating cell-to-cell signaling through tyrosine phosphorylation (Harari et al

and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling

Expression of SERPINB7 is upregulated in IgA nephropathy and mutations have been found to cause palmoplantar keratoderma

Vav1(Phospho Tyr174) Polyclonal Antibody, 50ul Funnels Interacts with the phosphorylated carboxyterminalThis gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T cell and B cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV 1.