Raf-1(Phospho Ser259) Polyclonal Antibody, 50ul Enzymes & Activity Assays Cytochrome P450 2E1 localizes to

Cytochrome P450 2E1 localizes to the endoplasmic reticulum and is induced by ethanol

This gene encodes a member of the sine oculis homeobox transcription factor family

This gene functions as a tumor suppressor gene in a number of common cancers

This protein is found to form a complex with MALT1

a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain

Raf-1(Phospho Ser259) Polyclonal Antibody, 50ul Enzymes & Activity Assays Cytochrome P450 2E1 localizes toThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.