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Rb Polyclonal Antibody, 100ul[BT-AP07686] Vessels and large extracellular loops containing

SKU: 24381194506

4.8
PLN123.75 PLN155.75

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Rb Polyclonal Antibody, 100ul[BT-AP07686] Vessels and large extracellular loops containingThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

and large extracellular loops containing multiple N-glycosylation sites

COL4A3 is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter

Studies of the rat counterpart suggest that the encoded protein may function as a receptor for adrenomedullin

Cyclin F encoded by CCNF belongs to the Fbxs class and it was one of the first proteins in which the F-box motif was identified

which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm

Rb Polyclonal Antibody, 100ul[BT-AP07686] Vessels and large extracellular loops containingThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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