Ob Polyclonal Antibody, 50ul[BT-AP12166] Recombinant Ab Production E3 ubiquitin-protein ligase which accepts

E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes

This gene has a mouse ortholog

It lacks alcohol dehydrogenase activity although by similarity it is considered a member of the zinc-containing alcohol dehydrogenase family

|PTM:Phosphorylation by PKB/AKT1 inhibits transcriptional activity and is responsible for cytoplasmic localization

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Ob Polyclonal Antibody, 50ul[BT-AP12166] Recombinant Ab Production E3 ubiquitin-protein ligase which acceptsThis gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses,