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StIp1 Polyclonal Antibody, 100ul[BT-AP08653] Sample Library Tubes Mutations in PARK2 are known

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StIp1 Polyclonal Antibody, 100ul[BT-AP08653] Sample Library Tubes Mutations in PARK2 are knownElongator complex protein 2 encoded by ELP2 is a core subunit of the elongator complex, a histone acetyltransferase complex that associates with RNA polymerase II. In addition to histone acetylation, the encoded protein effects transcriptional elongation and may help remodel chromatin.

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Description

Mutations in PARK2 are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease

Activation of this receptor induces cell-cell adhesion

Interacts with varicella-zoster virus IE62 protein and HIV-1 Vpr

Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35

Overexpression of this gene is associated with increased differentiation and proliferation in colorectal cancer

StIp1 Polyclonal Antibody, 100ul[BT-AP08653] Sample Library Tubes Mutations in PARK2 are knownElongator complex protein 2 encoded by ELP2 is a core subunit of the elongator complex, a histone acetyltransferase complex that associates with RNA polymerase II. In addition to histone acetylation, the encoded protein effects transcriptional elongation and may help remodel chromatin.

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