Rat Nuclear Factor Erythroid 2-related Factor 2, NRF2 ELISA Kit, 96T Monoclonal Antibody Preparation Usher syndrome 1D and nonsyndromic

Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene

including lipogenesis and cholesterogenesis

A mutation in this gene results in trismus-pseudocamptodactyly syndrome

part of the cadherin superfamily

Bile acids are the catabolic product of cholesterol metabolism

Rat Nuclear Factor Erythroid 2-related Factor 2, NRF2 ELISA Kit, 96T Monoclonal Antibody Preparation Usher syndrome 1D and nonsyndromicTranscription factor that plays a key role in the response to oxidative stress: binds to antioxidant response (ARE) elements present in the promoter region of many cytoprotective genes, such as phase 2 detoxifying enzymes, and promotes their expression, thereby neutralizing reactive electrophiles (PubMed: 16314513). In normal conditions, ubiquitinated and degraded in the cytoplasm by the BCR(KEAP1) complex. In response to oxidative stress,